On les retrouve aussi au niveau du conduit auditif externe du chien. Das Wissen über Malassezia Hefen und ihrer Rolle bei Krankheiten von Tieren hat sich bemerkenswert erweitert, vor allem seit den frühen 1990ern. Yeasts of Emerging Concern in Fungemia. Chez les chiens: - traitement et stabilisation de la dermatite séborrhéique associée à Malassezia pachydermatis et Staphylococcus intermedius. Histopathological features in dogs often comprise hyperkeratosis or parakeratosis, irregular epidermal hyperplasia and spongiosis that extends to hair follicle infundibulae, lymphocyte and granulocyte exocytosis, and a mixed, predominately lymphocytic, superficial perivascular or interstitial infiltrate with variable superficial dermal oedema. Il arrive que l’oreille dégage une odeur très désagréable en cas d’infection. Despite this, no correlation has been found between Malassezia‐specific serum IgG concentration and atopy patch test responses to the yeast in patients with atopic dermatitis.63, 197 It is therefore considered that determination of Malassezia‐specific IgG concentrations has little value in the diagnosis of Malassezia sensitization in atopic human patients.178, 197 However, concentrations of IgG4, a subtype that is induced in Th2 responses, are correlated with IgE concentrations in atopic patients with sensitivity to Malassezia sympodialis.205, In atopic dogs with or without cytological evidence of M. pachydermatis overgrowth, there are significantly higher serum titres of Malassezia‐specific IgG than those seen in healthy dogs.206 However, there was no significant difference between atopic dogs with or without Malassezia overgrowth. Chez le chien : traitement et stabilisation de la dermite séborrhéique associé à malassezia pachydermatis et staphylococcus intermédius. This is a paraneoplastic syndrome characterised by a generalised marked inflammatory exfoliation with patchy hair loss and easily epilated hair, and variably thickened skin which may be fissured or ulcerated. An unusual feature of this study was reported lack of relapse 150 days post‐treatment in all of the essential oil‐treated dogs. This may be considered to be the topical treatment of first choice, where available and locally approved, and when owners are able to apply the product effectively. The interactions between Malassezia yeasts and the skin of their hosts, and the factors which influence transition from commensal to pathogen, are the subject of intensive scientific endeavour, especially pertaining to the common pathogens of humans (M. globosa, M. sympodialis, M. restricta and M. furfur).33, 129 Comparative genomic studies following the sequencing of 14 Malassezia species have significantly advanced opportunities for understanding of the adaption of the genus to its limited ecological niches (mainly skin), elucidation of virulence attributes necessary for colonisation and infection, and identification of novel interventional targets for therapy.8 In particular, the novel description of Agrobacterium tumifaciens‐mediated transformation systems that allows for the insertion of transfer DNA and targeted gene deletion in M. furfur, M. sympodialis and M. pachydermatis, and thus analysis of individual gene function, is certain to revolutionise our understanding of the biology of this genus.130-132. Download Citation | Comparaison de deux posologies de kétoconazole pour le traitement de la dermatite à Malassezia chez le chien | 20 dogs with Malassezia dermatitis were included in this study. Lexamen cytologique cutané doit permet… Table S5. RCT‐B (10 dogs received terbinafine at either dose), 30 mg/kg once daily OR on two consecutive days/week, for 21 days, 8/10> 50% clinical improvement in both groups.